Watertight dural closure (WTDC) is traditionally regarded as standard practice in craniotomy, although postoperative cerebrospinal fluid (CSF) may still leak through small gaps and predispose to extradural fluid collection, incisional fistula, infection, and wound dehiscence. Non-watertight dural closure (non-WTDC), defined as low-tension approximation of the dural edges without pursuit of complete closure, may mitigate pressure gradients across the dura and reduce these complications in included cases. We applied a standardized non-WTDC technique in 40 consecutive patients undergoing elective supratentorial craniotomy for a range of supratentorial lesions, including tumors, arachnoid cysts, ruptured and unruptured aneurysms, subdural hematoma, and arteriovenous malformations. Three patients developed postoperative CSF collections; one resolved with conservative management, and two were successfully treated with secondary conversion to WTDC. No patient developed an incisional CSF fistula, meningitis, or wound breakdown. In this early experience, non-WTDC after supratentorial craniotomy appeared sufficient and safe in appropriately included patients and may offer practical advantages by simplifying dural reconstruction and obviating the need for dural grafts or sealants during the primary closure.