Babol University of Medical Sciences Caspian Journal of Surgery 3115-9087 1 1 2025 03 01 A rare case of Zinner syndrome and grade 3 varicocele 7 10 724983 10.22088/caspjs.2025.724983 EN Hamid Shafi Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran 0000-0002-3344-923X Morteza Nasiri Student Research Committee, Babol University of Medical Sciences, Babol, Iran 0000-0003-1416-5431 Ali Akbarzadeh Pasha Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran 0000-0002-2271-3154 Niusha Jamshidi Student Research Committee, Babol University of Medical Sciences, Babol, Iran 0009-0001-8621-2252 Ali Asghar Rezaei Student Research Committee, Babol University of Medical Sciences, Babol, Iran 0000-0003-2727-1639 Zahra Shafi Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran 0000-0001-9330-0851 Journal Article 2025 05 03 Zinner syndrome is an uncommon congenital disorder characterized by a triad of unilateral renal agenesis, ejaculatory duct obstruction, and ipsilateral seminal vesicle cyst. In this case, we presented a 27-year-old patient with left scrotal discomfort and varicocele grade 3 and Zinner syndrome and oligospermia who underwent inguinal varicocelectomy and the patient improved semen analysis and symptoms.Keywords: Zinner syndrome, Seminal vesicle cyst, Renal agenesis, Oligospermia, Varicocele<br>Zinner syndrome (ZS) is an uncommon congenital anomaly that exclusively affects males. The condition is characterized by a triad of anomalies: unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ejaculatory tract atresia (1). We present a case of a 27-year-old man with scrotal discomfort and varicocele in the physical examination and oligospermia and find Zinner syndrome in ultrasonography underwent inguinal varicocelectomy.<br>In this case, indication of varicocelectomy is scrotal discomfort in Zinner syndrome, had ejaculatory tract atresia but against to our expectation, semen fluid analysis improved. In this situation, (Zinner syndrome and varicocele) perform varicocelectomy help patient for infertility plan management. https://www.caspjs.com/article_724983_1bed5a18011e373c3cbfbce76e0ba9a8.pdf